Vol. 37. No. 1


NK/T-cell lymphoma, nasal type, γδ T-cell lymphoma, and CD8-positive epidermotropic T-cell lymphoma—clinical and histopathologic features, differential diagnosis, and treatment

Melissa Pulitzer, MD | Patricia L. Myskowski, MD | Patricia L. Myskowski, MD | Shamir Geller, MD
This review delivers up-to-date information about the clinical presentation, histopathologic features, differential diagnosis, and therapy of extranodal NK/T-cell lymphoma, nasal type, primary cutaneous gamma delta T-cell lymphoma, and primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma.

Histopathologic approach to epidermotropic lymphocytic infiltrates

Shyam S. Raghavan, MD | Jina Kim, MD, Phd
Herein, we review the wide array of epidermotropic T-cell lymphomas and discuss distinguishing features between these entities. We also offer an algorithmic approach utilizing histopathologic, immunophenotypic, and molecular techniques that can be used for analyzing an epidermotropic T-cell infiltrate in order to render a specific diagnosis.

Approach to dermal-based lymphoid infiltrates and proliferations

Yann Charli-Joseph, MD | Sonya Toussaint-Claire, MD | Carmen Lome-Maldonano, MD | Daniel Montante-Montes de Oca, MD | Carlo Ortiz-Hidalgo, MD

In this review we advocate a stepped histopathological approach for dermalbased lymphoid infiltrations, employing as key elements the general lymphocytic composition (relative B- versus T-cell ratio), coupled with the predominant cytomorphology (cell size) present.