Vol. 25. No. 1


Afros, dreadlocks, skinheads, hippies, spikes, braids, Samson, Goldilocks, Rapunzel, and “Hair” the musical? It would be difficult to underestimate the importance of hair in our society. Despite this, however, there are  relatively few physicians and scientists who devote their practice and research to the study of hair loss (alopecia). Nevertheless, in the last century enormous progress has been made in the diagnosis and treatment of many disorders that eventuate in alopecia.

Alopecia, Introduction

Shawn E Cowper, MD

This issue of Seminars in Cutaneous Medicine and Surgery is devoted to summarizing our current state of knowledge in
the diagnosis and management of hair loss.


Biology of the Hair Follicle: The Basics

Karoline Krause, MD

The mammalian hair follicle represents a unique, highly regenerative neuroectodermal– mesodermal interaction system that contains numerous stem cells. It is the only organ in the mammalian organism that undergoes life-long cycles of rapid growth (anagen), regression (catagen), and resting periods (telogen).


Office Diagnosis of Hair Shaft Defects

David A Whiting, ME, FACP, FRCP (Ed) | Lady C Dy, MD

Hair shaft abnormalities are fascinating and can provide a diagnostic challenge. Current knowledge of structural changes in hair has been amplified by scanning and transmission electron microscopy (SEM and TEM). PDF NOT AVAILABLE. Contact [email protected] for a copy of the article.


The Histopathology of Noncicatricial Alopecia

Grant Eudy, MD

During the past 2 decades, the use of transverse sections in the evaluation of scalp biopsy specimens has led to a better understanding of the histopathologic changes in both cicatricial and noncicatricial alopecia.