ADVANCES IN ACNE RESEARCH
Introduction
This issue of Seminars in Cutaneous Medicine and Surgery is devoted to summarizing some recent advances in acne research. I had set for myself 2 goals as guest editor of this issue: (1) to select topics that are at once timely, intriguing, and controversial; and (2) to introduce to the readership a few investigators who are making their mark in acne research. Their names may not be ones that the majority of the readership has heard in the past, but they are undoubtedly ones they are likely to hear in the near future.
Advances in Acne Research, Introduction
Welcome to the next generation of acne research.
Insights in the Pathogenic Potential of Propionibacterium acnes From Its Complete Genome
One of the long-lasting open questions in understanding acne is the role of the skin bacterium Propionibacterium acnes. Opinions within the scientific community diverge regarding the importance of this Gram-positive bacterium not only in acne but also in other P. acnes-associated diseases.
The Role of Toll-Like Receptors in the Pathophysiology of Acne
Acne vulgaris is a common cutaneous disorder of the pilosebaceous follicle, affecting more than 45 million people in the United States alone.
The Role of Inflammation in the Pathogenesis of Acne and Acne Scarring
The sequence of events involved in acne lesion initiation, augmentation, and resolution have eluded acne researchers.
Implications for the Role of Diet in Acne
This article will provide a review of the currently available literature on the association between diet and acne vulgaris as well as a discussion of the physiologic principles that may underlie this association.