Michael S. Kaminer

Guest Editor for the following articles:

Vol. 21. No. 2

Wound Closure Materials in the New Millennium

Gregg M Menaker, MD

MODERN DERMATOLOGIC SURGEONS often take wound closure materials for granted. On the eve of a new millennium, today’s surgeons can specifically tailor their choice of a wound closure material to the clinical situation at hand.

Vol. 28. No. 4

High-Intensity Focused Ultrasound Effectively Reduces Adipose Tissue

Afschin Fatemi, MD

Liposonix is considered to be a nonsurgical treatment for body contouring that uses
high-intensity focused ultrasound (HIFU) to disrupt adipocytes percutaneously. We wanted
to find out about its efficacy, effectiveness, and so forth. The technique delivers energy
across the skin surface at a relatively low intensity, but brings this energy to a sharp focus
in the subcutaneous fat. At the skin surface, the intensity of the ultrasound energy is low
enough so that no damage occurs. The focusing of the ultrasound beam at specific depths
beneath the epidermis, combined with proprietary application techniques, results in adipose
tissue disruption. Once adipocytes have been disrupted, chemotactic signals activate
the body’s inflammatory response mechanisms. Macrophage cells are attracted to the area
to engulf and transport the lipids and cell debris. This results in an overall reduction in local
adipose tissue volume. Our clinical and histologic studies will show exactly what happens
under the skin. We did a series of studies on gross pathology and histology, and we tried
to correlate these with the clinical results. The histologies show clearly that adipocytes are
disrupted by HIFU. The pathologies show the lesions, but they are always at a safe distance
from dermis or the epidermis. The correlation between focal depth, energy levels, and
clinical results is evident. The average circumference reduction after treatment of the
abdomen and waist is 4-5 cm. Liposonix turns out to be a safe and effective technique for
nonsurgical body sculpting by reduction of fat deposits.
Semin Cutan Med Surg 28:257-262 © 2009 Elsevier Inc. All rights reserved.

Vol. 22. No. 2

Psychosocial Issues and Their Relevance to the Cosmetic Surgery Patient

David B Sarwer, PhD | Ted A Grossbart, PhD

As the demand for cosmetic surgery continues to grow, it becomes increasingly important to understand the psychological factors that motivate people to seek surgery, and to determine if cosmetic surgery leads to psychological benefit.

Vol. 23. No. 4

The Histological Aspects of Fillers Complications

Thierry J Clerici, MD | Ute S Zimmerman, MD

The histological aspects of resorbable heterologous fillers (bovine collagen, acid hyaluronique), autologous fillers (lipofilling, dermis-fat graft), biodegradable fillers (New-Fill), and permanent fillers (silicone, Artecoll, Evolution, Aquamid, DermaLive, DermaDeep, Bioplastique, Paraffin) are described.