BOTULINUM toxins are exotoxins of the anaerobic spore-forming bacterium Clostridium Botulinum, and the causative agents of the severe food-borne illness botulism.

Botulinum toxin A has a wide variety of clinical applications, which are related by blockade of acetylcholine and often are related to abnormal muscle contractures.

Clinical trials with the type B toxin have recently established its efficacy in alleviating pain and excessive muscle contraction associated with cervical dystonia.