Cellulite is characterized by alterations to the skin surface, presenting as dimpled or
puckered skin of the buttocks and posterior and lateral thighs. It mainly affects women.
Cellulite occurrence is believed to be due to structural, inflammatory, morphological and
biochemical alterations of the subcutaneous tissue. However, its pathogenesis is not
completely understood. Topical treatments for cellulite include many agents, such those
that increase the microcirculation flow, agents that reduce lipogenesis and promote lipolysis,
agents that restore the normal structure of dermis and subcutaneous tissue, and
agents that scavenge free radicals or prevent their formation. There are many cosmetic and
medical treatments for cellulite. However, there is little clinical evidence of an improvement
in cellulite, and none have been shown to lead to its resolution. The successful treatment
of cellulite will ultimately depend upon our understanding of the physiopathology of
cellulite adipose tissue.
Semin Cutan Med Surg 30:167-170 © 2011 Elsevier Inc. All rights reserved.Cellulite is characterized by alterations to the skin surface, presenting as dimpled or
puckered skin of the buttocks and posterior and lateral thighs. It mainly affects women.
Cellulite occurrence is believed to be due to structural, inflammatory, morphological and
biochemical alterations of the subcutaneous tissue. However, its pathogenesis is not
completely understood. Topical treatments for cellulite include many agents, such those
that increase the microcirculation flow, agents that reduce lipogenesis and promote lipolysis,
agents that restore the normal structure of dermis and subcutaneous tissue, and
agents that scavenge free radicals or prevent their formation. There are many cosmetic and
medical treatments for cellulite. However, there is little clinical evidence of an improvement
in cellulite, and none have been shown to lead to its resolution. The successful treatment
of cellulite will ultimately depend upon our understanding of the physiopathology of
cellulite adipose tissue.
Semin Cutan Med Surg 30:167-170 © 2011 Elsevier Inc. All rights reserved.