Noninfectious Granulomatous Dermatitides: A Review of 8 Disorders (Part 3 of 3)

DERMATITIS

Noninfectious Granulomatous Dermatitides: A Review of 8 Disorders (Part 3 of 3)

Sep
2013
Vol. 32. No. 3
Alice B. Gottlieb, PhD | Ari M. Goldminz, MD

In this review we focus on 3 of the non-infectious granulomatous dermatitides, interstitial granulomatous drug reaction, rheumatoid nodules, and cutaneous sarcoidosis, with an overview of their clinical and histological presentations, differential diagnoses, and treatment options. The disorders we discuss are polymorphic in their clinical and histopathological presentations, follow chronic or undulating disease courses, and are typically recalcitrant to therapeutic interventions. Although the clinical history may be helpful, careful and thorough histopathological examination is required. Established treatment algorithms for these disorders are lacking, and very few randomized, placebo-controlled studies have been published. Future investigations should focus on the evaluation of larger cohorts, not only to establish treatment recommendations in randomized, placebo-controlled trials, but also to reach a greater understanding of disease pathogenesis and clinical-pathological presentation.
Semin Cutan Med Surg 32:e7-e11 © 2013 Frontline Medical Communications

PURCHASE NOW