COSMECEUTICALS: CURRENT TRENDS AND MARKET ANALYSIS
Botanicals and Anti-Inflammatories: Natural Ingredients for Rosacea
Sep
2011
Vol. 30. No. 3
Rosacea is a chronic inflammatory skin condition characterized by cutaneous hypersensitivity.
There are many therapeutic options available for the treatment of rosacea, but none are
curative. Since the pathogenesis of rosacea remains elusive, it is not surprising that no single
treatment is paramount and that many patients find therapies unsatisfactory or even exacerbating.
Treatments are prescribed to work in concert with each other in order to ameliorate the
common clinical manifestations, which include: papules and pustules, telangiectasias, erythema,
gland hypertrophy, and ocular disease. The most validated topical therapies include
metronidazole, azelaic acid, and sodium sulfacetamide-sulfur. Many other topical therapies,
such as calcineurin inhibitors, benzoyl peroxide, clindamycin, retinoids, topical corticosteroids,
and permethrin have demonstrated varying degrees of success. Due to the inconsistent results
of the aforementioned therapies patients are increasingly turning to alternative products
containing natural ingredients or botanicals to ease inflammation and remit disease. Additional
research is needed to elucidate the benefits of these ingredients in the management of rosacea,
but some important considerations regarding the natural ingredients with clinical data will be
discussed here.
Semin Cutan Med Surg 30:148-155 © 2011 Elsevier Inc. All rights reserved.
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